Price Drop Alert Recombinant Human Cd3d&cd3e Heterodimer (c-fc-flag&c-fc-6his) Save 85% Now [g7uhsyD3]

Recombinant Human CD3D & CD3E Heterodimer

The Recombinant Human CD3D & CD3E Heterodimer (C-Fc-Flag & C-Fc-6His) is a cutting-edge biotechnology product designed for advanced research in immunology and cell biology. This heterodimer, composed of CD3D and CD3E chains, plays a crucial role in the T cell receptor-CD3 complex, which is essential for antigen recognition and signal transduction pathways. With its unique C-Fc-Flag and C-Fc-6His tags, this product offers enhanced protein expression and purification capabilities, making it an invaluable tool for researchers in the field.

Product Properties and Specifications

This recombinant heterodimer is produced in HEK293 cells, ensuring high purity and stability. The sequence covers Phe22-Ala105 and Asp23-Asp126, with a calculated molecular weight of 37-39.2 kDa and an observed molecular weight of 40-60 kDa. The product is >95% pure, as determined by reducing SDS-PAGE, and contains <1.0 EU per μg of protein, ensuring minimal endotoxin contamination. Its formulation includes 5%-8% trehalose, mannitol, and 0.01% Tween 80, providing optimal storage and reconstitution conditions.

Practical Applications and Benefits

The Recombinant Human CD3D & CD3E Heterodimer is a versatile research tool with numerous applications. It can be used to study T cell signaling, antigen recognition, and immune responses. Researchers in immunology, oncology, and virology can benefit from this product to advance their studies on T cell biology and its role in disease processes. The high purity, specificity, and ease of use make this heterodimer an indispensable component of any laboratory looking to delve into the complexities of the immune system.