All-in-one Recombinant Human Cdnf Protein(n-his) Kit [dQHugKkI]

High-Quality Recombinant Human CDNF Protein (N-His)

Our Recombinant Human CDNF protein (N-His) is a premium product designed for researchers and scientists in the field of neuroscience and neurodegenerative diseases. This protein is produced through a recombinant expression system in E. coli, ensuring high purity and consistency. With a calculated molecular weight of 19.3 kDa and an observed molecular weight of 18 kDa, this protein is ideal for various experimental applications.

Key Features and Specifications:

• Purity: > 98% as determined by reducing SDS-PAGE.
• Endotoxin: < 0.1 EU per μg of the protein as determined by the LAL method.
• Expression Host: E. coli.
• Sequence: Gln 27-Leu 187.
• Accession: Q49AH0.

Applications and Benefits:

Recombinant Human CDNF protein (N-His) is a valuable tool for studying the role of CDNF in various neurological disorders, particularly Parkinson's disease. CDNF, also known as ARMETL1, is a novel neurotrophic factor with strong trophic activity on dopaminergic neurons. This protein has been shown to protect and restore the function of dopaminergic neurons in rat models of Parkinson's disease, making it a promising candidate for therapeutic applications. Additionally, CDNF is expressed in brain regions that undergo cocaine-induced neuroplasticity, making it a valuable tool for studying addiction and neuroplasticity.