Verified Recombinant Human Hmgb1 Protein(n-his)(active) (top Rated) [f1TBj25F]

Recombinant Human HMGB1 Protein (N-His) (Active)

Discover the power of recombinant human HMGB1 protein (N-His) (active) with its exceptional purity and bioactivity. This product is a high-quality recombinant protein, derived from E. coli expression system, offering a reliable source for research and development applications. With a purity of over 98% as determined by reducing SDS-PAGE, this protein is suitable for various experiments and assays.

Key Features and Specifications

This recombinant HMGB1 protein carries a C-His tag, providing convenient purification and detection. It has a calculated molecular weight of 25.7 kDa and an observed molecular weight of 35 kDa. The protein sequence covers Met 1-Glu 215 and is encoded by the P09429 gene. Its bio-activity is measured by its ability to induce TNF alpha in RAW264.7 cells, with an ED₅₀ of <10 μg/mL. This active protein is a valuable tool for studying the role of HMGB1 in inflammatory responses and cellular signaling pathways.

Applications and Benefits

The recombinant human HMGB1 protein (N-His) (active) is a versatile tool for researchers in the fields of immunology, inflammation, and molecular biology. Its high purity and bioactivity make it ideal for various applications, including in vitro assays, cell culture experiments, and ELISA kits. The product is also suitable for generating monoclonal antibodies and studying the interaction between HMGB1 and its receptors. With its convenient formulation and storage conditions, this protein is a valuable addition to any laboratory's toolkit.